I don’t mean to sound like a heretic, but here goes.
I have an OB-3 Twanger that I purchased here, and I love it. However, I’m getting into clawhammer and two-finger thumb lead styles. Can I remove the resonator on the Twanger without messing up the excellent set-up work that Jake and Co. did on the instrument? I believe it’s as simple as removing the screws and the flange, but I haven’t done it on the Twanger yet and I don’t wanna mess it up.
Simply removing the resonator shouldn’t hurt your Twanger or change the setup. But don’t expect a classic clawhammer sound as a result. The head material and tension, bridge design, string height, and most importantly the tone ring are all designed to give a Scruggs style sound. A good clawhammer open back will have either a scoop or higher strings (typically with a taller bridge), a natural skin head with a warmer tension, and either a wood ring or another more muted design (like a simple brass ring). Making any of these changes will likely mess up the great Twanger sound. With all that said, though, Steve Martin often plays clawhammer with a resonator banjo. It just has a brighter clawhammer style that sounds different but really great. So I’d recommend keeping your Twanger as is and simply playing your clawhammer style closer to the neck than you’d typically do for Scruggs style. If you want a classic old time clawhammer banjo sound, Dave Dillard makes fantastic sounding banjos. Just my two cents worth of opinion. Regardless what you decide, enjoy the journey.
Sweet. I figured the tone ring would be an issue, but I didn’t stop to consider the height of the bridge. I’ve had a look at Dave’s banjos and they are beautiful instruments, but I recently shelled out for a Nate Calkins 12" openback. Maybe next time. 
How many banjos does one person need? Just one more.
Thanks for the feedback.